Mary Anderson, PhD
Articles
Mary E. Anderson, 鈥淎ssays of the Enzymes of Glutathione Biosynthesis鈥, Analytical Biochemistry, in press, 2021.c.
Mary E. Anderson, Michael Marks, Thomas R. Cundari, 鈥淏ifunctional activation of methane by bioinspired transition metal complexes. A simple methane protease model鈥, Computational and Theoretical Chemistry 2021, 1198, 113180.
Mary E. Anderson, Beno卯t Bra茂da, Philippe C. Hiberty, Thomas R. Cundari, 鈥淩evealing a Decisive Role for Secondary Coordination Sphere Nucleophiles on Methane Activation鈥, Journal of the American Chemical Society (JACS) 2020, 142, 6, 3125-3131.
T. R. Brown, Drummond, M.L., Barelier, S., Crutchfield, A.S., Dinescu, A., Slavens, K.D., Cundari, T.R., and M.E. Anderson, 鈥淎spartate 458 of Human Glutathione Synthetase is Important for Cooperativity and Active Site Structure鈥, Biochem. Biophys. Res. Commun., 411, 536-42, 2011.
K. A. Slavens, Brown, T.R., Barakat, K.A., Cundari, T.R., and M.E. Anderson, 鈥淰aline 44 and Valine 45 of Human Glutathione Synthetase are Key for Stability and Negative Cooperativity鈥, Biochem. Biophys. Res. Commun., Biochem. Biophys. Res. Commun., 410, 597-601, 2011.
Dinescu, A., Brown, T.R., Barelier, S., Cundari, T.R., and M.E. Anderson, 鈥淭he Role of the Glycine Triad in Human Glutathione Synthetase鈥, Biochem. Biophys. Res. Commun., 400, 511-16, 2010.
Dinescu, A., Anderson, M.E. and Cundari, T.R. 鈥淐atalytic Loop Motion in Human Glutathione Synthetase: A Molecular Modeling Approach鈥, Biochem Biophys. Res. Communications, 353, 450-456, 2007.
Dinescu, A., Cundari, T.R., Bhansali, V.S., Luo, J.-L., and Anderson, M.E., 鈥淔unction of Conserved Residues of Human Glutathione Synthetase: Implications for the ATP-grasp Enzymes鈥, Journal of Biological Chemistry, 279:22412-21, 2004.
Njalsson, R., Carlsson, K., Bhansali, V., Luo, J.-L., Nilsson, L., Ladenstein, R., Anderson, M., Larsson, A., and Norgren, S., 鈥淗uman Hereditary Glutathione Synthetase Deficiency: Kinetic Properties of Mutant Enzymes鈥, Biochemical Journal, 381(Pt 2):489-94, 2004.
Njalsson, R., Norgren, S., Larsson, A., Huang, C.-s., Anderson, M.E, Luo, J.-L., 鈥淐ooperative Binding of g-Glutamyl Substrate to Human Glutathione Synthetase鈥, Biochem. Biophys, Res. Commun, 289, 80-84, 2001
Dalhoff, K., Laursen, H., Bangert, K., Poulsen, H.E., Anderson, M.E. and Grunnet, N. and N. Tygstrup, 鈥淎utoprotection in Acetaminophen Intoxication in Rats: The Role of Liver Regeneration鈥, Pharmacol. Toxicol 88, 135-141, 2001.
Kruse, P., Anderson, M.E. and Loft, S., 鈥淢inimum Signs of Oxidative Stress During Intermediate Acute Pancreatitis in Rats鈥, Free Radical Biology and Medicine 30, 309-317, 2001.
Luo, J-L, Huang, C-S, Babaoglu, K. and Anderson, M.E., 鈥淣ovel Kinetics of Mammalian Glutathione Synthetase: Characterization of g-Glutamyl Substrate Cooperative Binding鈥, Biochem. Biophys. Res. Commun. 275, 577-581, 2000.
M.E. Anderson and Luo, J.L., 鈥淕lutathione Therapy: From Prodrugs to Genes鈥, Seminars in Liver Disease 18, 415-424, 1998.
M.E. Anderson. 鈥淕lutathione: an overview of biosynthesis and modulation鈥, Chemico-Biological Interactions 111-112, 1-14, 1998.
Hochwald, S.N,, Harrison, L.E., Anderson, M.E., Rose, D.M., and Burt, M.E., 鈥済-Glutamyl Transpeptidase Mediation of Tumor Glutathione Utilization鈥, J Natl. Cancer Inst 88, 193-107, 1996.
Ikeda, Y. Fujii, J., Anderson, M.E., Taniguchi, N. and Meister, A., 鈥淚nvolvement of Ser-451 and -452 in the Catalysis of Human g-Glutamyl Transpeptidase鈥, J. Biol. Chem. 270, 22223-22228, 1995.
Huang, C.-S., He, W., Meister, A., and Anderson, M.E.: 鈥淕lutathione Synthetase鈥 Proc. Natl. Acad. Sci. 92, 1234-1236, 1995.
S. Boesgaard, J. Aldershvile, H.E. Poulsen, S. Loft, M.E. Anderson, and A. Meister: 鈥淣itrate Tolerance In Vivo Is Not Associated with Depletion of Arterial or Venous Thiol Levels鈥, Circulation Research, 74, 115 120, 1994.
E.J. Levy, M.E. Anderson, and A. Meister: 鈥淭ransport of Glutathione Diethyl Ester into Human Cells鈥, Proc. Natl. Acad. Sci., 90, 9171-9175, 1993.
E.J. Levy, M.E. Anderson, and A. Meister: 鈥淥n the Synthesis and Characterization of N-Formyl Glutathione and N-Acetyl Glutathione鈥, Anal. Biochem., 214, 135-137,1993.
C.-s. Huang, Long-sen Chang, M.E. Anderson, and A. Meister: 鈥淎mino Acid Sequence and Function of the Light Subunit of Rat Kidney g-Glutamylcysteine Synthetase鈥, J. Biol. Chem., 268, 20578-20583, 1993.
C.-s. Huang, M.E. Anderson, and A. Meister: 鈥淐atalytic and Regulatory Properties of the Heavy Subunit of Rat Kidney 0-Glutamylcysteine Synthetase, Journal of Biological Chemistry, 268, 19675-19680, 1993.
S. Boesgaard, H.E. Poulsen, J. Aldershvile, S. Loft, M.E. Anderson, and A. Meister: 鈥淎cute Effects of Nitroglycerin Depend on Both Plasma and Intracellular Vascular Sulfhydryl Compound Levels In Vivo. Effect of Agents with Different Sulfhydryl Modulating Properties鈥, Circulation 87, 547-553, 1993.
A.K. Godwin, A. Meister, P.J. O鈥橠wyer, C.-S. Huang, T.C. Hamilton, and M.E. Anderson: 鈥淗igh Resistance to Cisplatin in Human Ovarian Cancer Cell Lines is Associated with Marked Increase of Glutathione Synthesis鈥, Proc. Natl. Acad. Sci, 89, 3070-3074, 1992.
T. Kalebic, A. Kinter, G. Poli, M.E. Anderson, A. Meister, and A.S. Fauci: 鈥淪uppression of HIV Expression in Chronically Infected Monocytic Cells by Glutathione, Glutathione Ester, and N-Acetyl Cysteine鈥, Proc. Natl. Acad. Sci., U.S., 88, 896-990, 1991.
M.E. Anderson, A. Naganuma, and A. Meister: 鈥淧rotection Against Cisplatin Toxicity By Administration of Glutathione Ester鈥, FASEB Journal, 4 (14), 3251-3255, 1990.
Naganuma, M.E. Anderson, and A. Meister: 鈥淐ellular Glutathione is a Determinant of Sensitivity to Mercuric Chloride Toxicity; Prevention of Toxicity by Giving Glutathione Monoester鈥, Biochemical Pharmacology, 40, 693-697,1990.
M. Suthanthiran, M.E. Anderson, V. K. Sharma, and A. Meister: 鈥淕lutathione Regulates Activation-Dependent DNA Synthesis in Highly Purified T lymphocytes stimulated via CD2 and CD3 Antigens鈥, Proc. Natl. Acad. Sci., U.S., 87, 3343-3347, 1990.
M.E. Anderson, A. Meister, 鈥淕lutathione Monoesters鈥, Anal Biochem 183, 16-20, 1989.
M.E. Anderson, M. Underwood, R.J. Bridges and A. Meister: 鈥淕lutathione Metabolism at the Blood-Cerebrospinal Fluid Barrier鈥, FASEB Journal 3, 2527-2531, 1989.
W.R. Moore, M.E. Anderson, A. Meister, K. Murata and A. Kimura: 鈥淚ncreased Capacity for Glutathione Synthesis Enhances Resistance to Radiation in Escherichia coli: A Possible Model for Mammalian Cell Protection, Proc Natl. Acad Sciences, 86, 1461-1464, 1989.
M.E. Anderson and A. Meister: 鈥2-Oxo-thiazolidine-4-carboxylic acid and Mouse Brain Cysteine and Glutathione Levels鈥, FASEB Journal 3, 1632-1636, 1989.
M.B. Astor, M.E. Anderson, Meister, A.: 鈥淩elationship Between Intracellular GSH Levels and Hypoxic Cell Radiosensitivity鈥, J. Pharm. Therapeutics, 39, 115-121, 1988.
R.K. Singhal, M.E. Anderson and A. Meister: 鈥淕lutathione, a First Line of Defense Against Cadmium Toxicity鈥, FASEB Journal 1, 220-223, 1987.
M.E. Anderson and A. Meister: 鈥淚ntracellular-Delivery of Cysteine鈥, Methods in Enzymology 143, 313 325, 1987.
M.E. Anderson and A. Meister: 鈥淚nhibition of g-Glutamyl Transpeptidase and Induction of Glutathionuria by g-Glutamyl Amino Acids鈥, Proc. Natl. Acad. Sci, 83, 5029-32, 1986.
A. Meister, M.E. Anderson and 0. Hwang: 鈥淚ntracellular Cysteine and Glutathione Delivery Systems鈥, Journal of the American College of Nutrition, 5, 137-157, 1986.
Anderson, M.E., F. Powrie, R.N. Puri and A. Meister: 鈥淕lutathione Monoethyl Ester: Preparation, Uptake by Tissues, and Conversion to Glutathione鈥, Archives of Biochem. Biophys, 239, 538-548, 1985.
V.P. Wellner, M.E. Anderson, R.N. Puri, G.L. Jensen and A. Meister: 鈥淩adioprotection by Glutathione Ester; Transport of Glutathione Ester into Human Lymphoid Cells and Fibroblasts鈥, Proc. Natl. Acad, Sci. U.S., 81, 4732-4735, 1984.
M.E. Anderson and A. Meister: 鈥淭ransport and Direct Utilization of g-Glutamylcyst(e)ine for Glutathione Synthesis鈥, Proc. Natl. Acad. Sci., U.S., 80, 707-711, 1983.
M.E. Anderson, R.D. Allison and A Meister: 鈥淚nterconversion of Leukotrienes Catalyzed by Purified g Glutamyl Transpeptidase: Concomitant Formation of Leukotriene D4 and g-Glutamyl Amino Acids鈥, Proc. Natl. Acad. Sci., U.S., 79, 1088-1091, 1982.
R.L. Beamer, O.W. Griffith, J.D. Gass, M.E. Anderson and A. Meister: Interaction of L- and D-3Amino-l-chloro-2-pentanone with g-Glutamylcysteine Synthetase鈥, J. Biol. Chem. 255, 11,73211,736, 1980.
M.E. Anderson, R.J. Bridges and A. Meister: 鈥淒irect Evidence for Inter-Organ Transport of Glutathione and that the Non-Filtration Renal Mechanism of Glutathione Utilization Involves g-Glutamyl Transpeptidase鈥, Biochem Biophys Res Comm 96, 848-853, 1980.
M.E. Anderson and A. Meister: 鈥淒ynamic State of Glutathione in Blood Plasma鈥, Journal of Biological Chemistry 255, 9530-9533, 1980.
O.W. Griffith, M.E. Anderson, and A. Meister: 鈥淚nhibition of Glutathione Biosynthesis by Prothionine Sulfoxjmine (S-n-Propyl Homocysteine Sulfoximine), A Selective Inhibitor of g-Glutamylcysteine Synthetase鈥, J. Biol. Chem. 2 54, 1205-1210, 1979.
Book Chapters and Chapters in Series
Anderson, ME and Stopper, A, 鈥淕lutathione鈥, in Encyclopedia of Biological Chemistry, 3rd ed. (ed J. Jez), Elsevier, Oxford, UK, in press 2021.
Larsson, A., Ristoff, E. and Anderson, M.E., 鈥淕lutathione Synthetase Deficiency and Other Disorders of the g-Glutamyl Cycle鈥 in: Metabolic Basis of Inherited Disease, Online (genetics.accessmedicine.com) (eds. Scriver, C.R., Beaudet, A.L., Sly, W.S and Valle, D.) McGraw Hill, NY, 2005
Larsson, A. and Anderson, M.E., 鈥淕lutathione Synthetase Deficiency and Other Disorders of the g Glutamyl Cycle鈥 in: Metabolic Basis of Inherited Disease, 8th ed. (eds. Scriver, C.R., Beaudet, A.L., Sly, W.S., Valle, D.) McGraw Hill, NY, pp. 2205-16, 2001.
Anderson, M.E.: 鈥淢odulation of Glutathione鈥; in Handbook of Synthetic Antioxidants, eds. Packer, L. and Cadenas, E., pp. 321-338, 1997, Marcel Dekker, Inc.
Anderson, M.E.: 鈥淕lutathione鈥; in Free Radicals a Practical Approach, eds. Punchard, N.A. and Kelly, F.J., Oxford University Press, New York, pp.213-226, 1996.
Anderson, M.E.: 鈥淕lutathione and Glutathione Delivery Compounds鈥; Advances in Pharmacology 38, 65 78, 1997.
E.J. Levy, M.E. Anderson, and A. Meister: 鈥淧reparation and, Use of Glutathione Diesters鈥, Methods in Enzymology, 504-511, 1994.
M.E. Anderson, E.J. Levy, and A. Meister: 鈥淧reparation and Use of Glutathione Monoesters鈥, Methods in Enzymology, 511-517, 1994.
M.E. Anderson: 鈥淓nzymatic and Chemical Methods for the Determination of Glutathione鈥, in Coenzymes and Cofactors: Glutathione, D. Dolphin, R. Poulson, and 0. Avramovic, eds, John Wiley, New York, pp. 339-366,1989.
M.E. Anderson: 鈥淒etermination of Glutathione and Glutathione Disulfide in Biological Samples鈥 Methods in Enzymology, 113, 548-555, 1985.
M.E. Anderson and A. Meister: 鈥淧reparation of g-Glutamyl Amino Acids by Chemical and Enzymatic Methods鈥, Methods in Enzymology 113, 555-564, 1985.
M.E. Anderson: 鈥淒etermination of Glutathione in Biological Tissues鈥, Handbook for Oxygen Radical Research (A. Greenwald, Ed.), CRC Press, Boca Raton, Fla., 317-323, 1985.
A. Meister and M.E. Anderson: 鈥淕lutathione鈥, Annual Reviews of Biochemistry, 52, 711-760, 1983.
Patents
US #6,127,165, Rat glutathione synthetase gene; C-s Huang, A Meister, ME Anderson
US # 5,869,456, Use of glutathione diesters; E.J. Levy, M.E. Anderson, A. Meister
US # 5,747,329, Glutamylcysteine synthetase light subunit; C.-s. Huang, M.E. Anderson, A. Meister
US # 5,476,966, Method for depletion of glutathione; M.E. Anderson and A. Meister
US # 5,464,825, Raising glutathione equivalent levels using N-acyl glutathione monoesters; E.J. Levy, M.E. Anderson, A. Meister
US #4,758,551, Methods for combating renal toxicity due to metals or nephrotoxic drugs and for selectively modulating in vivo formation of leukotriene types; M.E. Anderson, A. Meister
Presentations at Professional Meetings: (Abstracts since 1998 - current)
Thomas R. Cundari and Mary E. Anderson 鈥淐atalyst Design: What Can We Learn from Enzymes and Biological Modeling?鈥 VIth International Workshop on Quantum Systems in Chemistry and Physics (QSCP-XVI), Kanazawa, Japan, September 2011.
T. Brown, K. Slavens, M. DeJesus, A. Crutchfield, B. Shrestha, M.L. Drummond, S. Barelier, A. Dinescu, T.R. Cundari, M.E. Anderson. 鈥淔unction of Aspartate 458 in Human Glutathione Synthetase鈥, American Society for Biochemistry and Molecular Biology Annual Meeting, April 2011 Washington, D.C. [T. Brown, Graduate Student Travel Award from ASBMB].
K. Slavens, B. Shrestha, T. Brown, K. Barakat, T.R. Cundari , and M.E. Anderson. 鈥淕lutathione Synthetase: Hydrophobic Interactions and Stability鈥, American Society for Biochemistry and Molecular Biology Annual Meeting, April 2011 Washington, D.C.
A. Crutchfield, T. Brown, K. Slavens, M. De Jesus, A. Graves, B. Shrestha, A. Dinescu, S. Barelier, T.R. Cundari, and M.E. Anderson, 鈥淎nalysis of Aspartate 458 in the A Loop of Glutathione Synthetase鈥, ACS SWRM meeting, October 2011, Austin
T.R. Cundari and M.E. Anderson, 鈥淩ole of Catalytic Loops in Glutathione Synthetase Negative Cooperativity鈥, ACS SWRM meeting, October 2011, Austin
K. Selman, M. De Jesus, T.R. Cundari, M.E. Anderson, Glutathione Synthetase: Dimer Interface and Negative Cooperativity March 2010 San Francisco ACS National meeting
T. Brown, S. Barelier, A. Dinescu, T.R. Cundari, M.E. Anderson, The A-loop of Human Glutathione Synthetase; March 2010 San Francisco ACS National meeting
T. Brown, A. Dinescu, K. Slavens, M. DeJesus, T.R. Cundari, M.E. Anderson, Unusual Glycine Triad Key for GSH Synthetase Activity, poster to be presented at the national meeting of the American Society of Biochemistry and Molecular Biology, New Orleans, LA., April 17-22, 2009.
M.E. Anderson, T. Brown, S. Barelier, A. Dinescu, T.R. Cundari, C-Terminal Residues of Glutathione Synthetase: A Mutational Analysis, poster at the Southwest Regional American Chemical Society Meeting in Little Rock, October 1 to 4, 2008.
T. Brown, S. Barelier, A. Dinescu, T.R. Cundari, M.E. Anderson, C-Terminal Residues of Glutathione Synthetase, poster at the American Society of Biochemistry and Molecular Biology National meeting, April 2008 [note: T. Brown received an Undergraduate Research Achievement Award Poster Competition, and a Undergraduate Competitive Travel Award.
K. Selman, T. Brown, A. Dinescu, M.E. Anderson, Substrate Loop in Glutathione Synthetase: a mutational analysis, poster at the American Society of Biochemistry and Molecular Biology National meeting, April 2008.
T. Brown, Sarah Barelier, Adriana Dinescu, T. R. Cundari, M.E. Anderson, C-Terminal Residues of Human Glutathione Synthetase: A Mutational Study, Platform Oral presentation at the Dallas Fort Worth American Chemical Society Meeting-in-Miniature April 2008. Undergraduate [note: T. Brown received 3rd place award of excellence in the undergraduate division.
K. Selman, T. Brown, M.E. Anderson; Glutathione Synthetase: Substrate Loop Mutational Analysis, poster at the Student Research Symposium at Texas Woman鈥檚 University, April 2008.
T. Brown, A. Dinescu, Sarah Barelier, T. Cundari, M.E. Anderson ; C-Terminal Interactions of Human Glutathione Synthetase, poster at the Student Research Symposium at Texas Woman鈥檚 University, April 2008.
M.E. Anderson. S. Hernandez, M.J. Carter, T.R. Cundari, A. Dinescu, S. Barelier, 鈥淢odeling of Human Glutathione Synthetase: An ATP-Grasp Enzyme鈥, Talk at the Southwest Regional Meeting of the American Chemical Society in Lubbock, TX, November 2007.
M.E. Anderson, T.R. Cundari, A. Dinescu, M. Carter, S. Hernandez, 鈥淢odeling of human glutathione synthetase: An ATP-Grasp enzyme鈥, at the national meeting of the American Chemical Society in Chicago, March 2007.
T. Brown, A. Dinescu, T. Cundari, M.E. Anderson, 鈥淎-Loop Residues in Glutathione Synthetase鈥 for the national meeting of the American Society of Biochemistry and Molecular Biology in Washington, D.C., April 2007.
M. Carter, K. Barakat, T.R. Cundari, and M.E. Anderson, "Subunit Interactions of Human Glutathione Synthetase", the national meeting of the American Society of Biochemistry and Molecular Biology in Washington, D.C., 2007.
K. Selman, T. Brown, A. Dinescu. M.E. Anderson, T. Cundari Human, "Glutathione Synthetase Substrate Loop Analysis", for the national meeti
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